Figure 6: Effect of miR 21 5p on senescence and immune response in mesenchymal stem cells from the pre pubertal group.(A) Western blot analysis of LMNA/C and Wnt5a in the pre pubertal MSC group with or without inhibition of miR 21 and their densitometry analysis normalized with respect to tubulin. (B) Western blot analysis of TLR4, mTOR and HMGB1 in the pre pubertal MSC group with or without inhibition of miR 21 and their densitometry analysis normalized with respect to tubulin. (C) Western blot analysis of the AKT pathway in the pre pubertal MSC group with or without inhibition of miR 21 and their densitometry analysis normalized with respect to tubulin or actin.
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Figure 1 shows the distribution of p53 mutations in these codons in our series and in the current data base of human colon cancers.4 Owing to the small number of mutations in each hot spot codon, our material was combined with other rectal cancers (combined frequencies are indicated by open circles in the figure) recorded in the current data base.4 Overall, codon 175 mutations are less common (p v 107 of 980, including rectosigmoid cancer).Frequency of p53 mutations in five hot spot codons in rectal cancer among Finnish women and in colon cancer (current data base 4 ). The open circles represent frequencies for rectal cancer in combined material (our study plus the current data base with specified rectal cancer). Hatched columns, rectal cancers; filled columns, colon cancers..
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But there was much to celebrate on the field for France as N’Golo Kante marked his first start by scoring the opener, continuing the fine form that has seen Leicester surprisingly surge to the top of the Premier League. Mario Goetze, who hasn’t played for Germany since sustaining a groin injury in October, marked his international return by heading in the second goal. The shirts read: “In memory of all victims, Brussels 22.03.2016.”In the game, first half goals from Nani and Cristiano Ronaldo secured Portugal’s victory, while Romelu Lukaku pulled one back for a lackluster Belgium side after the break with a header.(This story has not been edited by NDTV staff and is auto generated from a syndicated feed.).
